HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Methyl-3,9-diazabicyclo[4.2.1]nonane → 1-Vinyl-6-fluoro-7-(9-methyl-3,9-diazabicyclo[4.2.1]non-3-yl)-1,4-dihydro-4-oxo-3-quinoline carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Methyl-3,9-diazabicyclo[4.2.1]nonane | HCID 13973730 | — |
| Reactant | 6,7-Difluoro-1-vinyl-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid | HCID 15140256 | — |
| Product | 1-Vinyl-6-fluoro-7-(9-methyl-3,9-diazabicyclo[4.2.1]non-3-yl)-1,4-dihydro-4-oxo-3-quinoline carboxylic acid | HCID 14328927 | 44.7% |
Reaction Steps
The title comound was prepared in 44.7% yield according to example 8 by reacting 6,7-difluoro-1-vinyl-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid with 9-methyl-3,9-diazabicyclo[4.2.1]nonane, m.p. 214°-215° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04775668 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-6ba9dbe1321f4d05984afb63be0e4251 |
| Source note | uspto-grants-1988_10 |