HCID 14009969, compound → HCID 14009973, compound

Participants

Reaction Steps

A solution of 4-methyl-2-[2-(4-nitrophenoxy)ethyl]-5-phenyloxazole (12.5 g) in methanol (150 ml) was subjected to catalytic reduction in the presence of 5% Pd-C (wet, 3.0 g). The catalyst was then filtered off and the filtrate was concentrated to give 2-[2-(4-aminophenoxy)ethyl]-4-methyl-5-phenyloxazole (11.0 g, 97.3%). Recrsytallization from ethanol gave colorless needles. M.p. 106°-107° C.

Provenance & Evidence