HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 86741570, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1-Acetyl-4-(2',4'-difluorobenzoyl)piperidine | HCID 2740707 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86741570 | HCID 86741570 | 79.2% |
Reaction Steps
A solution of 15.0 g of 4-(2,4-difluorobenzoyl)-1-acetylpiperidine, 6.9 g of hydrazine hydrate and 140 ml of ethanol was heated under reflux for 4 hrs. The ethanol was removed in vacuo to give a solid. The solid was triturated with water, filtered and dried to yield 12.5 g (64%) of 1-acetyl-4-(2,4-difluorobenzoyl)piperidine hydrazone, mp 139°-142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04775761 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-513f445da444484795f1bab684016dec |
| Source note | uspto-grants-1988_10 |