Diazomethane → Methyl cyclohexanepropionate

Participants

Reaction Steps

To an ice-cooled and stirred solution of 3-cyclohexylpropionic acid (5.0 g, 32.1 mmol) in 30 ml of ether was added an excess solution of diazomethane in ether. After concentration, the residue was distilled under reduced pressure to give a colorless transparent liquid of methyl 3-cyclohexylpropionate (4.8 g, 28.2 mmol, yield 88%, b.p. 95°-99° C./8 mmHg), which was assigned the structure by the following data:

Provenance & Evidence