Dicyclohexylcarbodiimide → HCID 13799417, compound

HRID 867833Notes

Reaction equation

HRID 867833 reaction equation
[CH:1]1(N=C=NC2CCCCC2)CCCCC1.[CH2:16]([S:23][C:24]1[CH:32]=[CH:31][C:27]([C:28]([OH:30])=[O:29])=[C:26]([C:33]2[NH:34][C:35](=[O:42])[C:36]([CH:39]([CH3:41])[CH3:40])([CH3:38])[N:37]=2)[N:25]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(Cl)Cl>[CH3:1][O:29][C:28](=[O:30])[C:27]1[CH:31]=[CH:32][C:24]([S:23][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[N:25][C:26]=1[C:33]1[NH:34][C:35](=[O:42])[C:36]([CH:39]([CH3:40])[CH3:41])([CH3:38])[N:37]=1

Participants

4

Reactant 2

HCID 10868DicyclohexylcarbodiimideHCID 13799415HCID 13799415, compound

Product 1

HCID 13799417HCID 13799417, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.0 g (0.005 mol) dicyclohexylcarbodiimide and 2.0 g (0.005 mol) 6-benzylthio-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-nicotinic acid are dissolved in 30 ml methylene chloride, then stirred for 4 hours at room temperature and allowed to stand overnight. The reaction mixture is filtered and the filtrate is then compressed. The oily residue crystallizes after a while.

Workup

  1. waitto stand overnight
  2. filtrationThe reaction mixture is filtered
  3. customThe oily residue crystallizes after a while

Sources & evidence

ORD record
ord-9a9ebb158d744152be0f2b4527536009
Source dataset
uspto-grants-1988_10
Patent number
US04776876

Reaction notes

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