Water → N,N,2-Trimethyl-3-thiophenemethanamine

HRID 867925Notes

Reaction equation

HRID 867925 reaction equation
[CH3:1][N:2]([CH3:11])[C:3]([C:5]1(C)[CH:9]=[CH:8][S:7][CH2:6]1)=O.[H-].[Al+3].[Li+].[H-].[H-].[H-].O.[CH2:19](OCC)C>>[CH3:1][N:2]([CH3:11])[CH2:3][C:5]1[CH:9]=[CH:8][S:7][C:6]=1[CH3:19]

Participants

5

Reactant 4

HCID 962WaterHCID 3283Diethyl Ether2×HCID 21226445Aluminium lithium hydrideHCID 70417769HCID 70417769, compound

Product 1

HCID 10374728N,N,2-Trimethyl-3-thiophenemethanamine

Procedure

A solution of N,N,3-trimethyl-3-thiophene carboxamide (1.3 g) in dry diethylether (50 ml) was added to a slurry of lithium aluminium hydride (0.3 g) in dry diethylether (100 ml) at room temperature. The mixture was stirred for 1 hour and then water was added. The mixture was filtered and the filtrate was evaporated to give the title compound (0.75 g) as a colourless oil. The picrate salt was formed in ethanol m.p. 155°.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-a1eda82a58f64af9b1d13b51cce10aa4
Source dataset
uspto-grants-1988_10
Patent number
US04777179

Reaction notes

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