HCID 53755082, compound → HCID 14257704, compound

Participants

Reaction Steps

7,8-Dichloro-6-methoxy-2-propylidene-1-tetralone (1.1 g) in 50 ml of 2-propanol and 150 mg of 5% Pd/C catalyst, were placed in a Parr apparatus and hydrogenated at 30 psi for 20 minutes. The reaction mixture was warmed slightly, the catalyst filtered, rinsed with 2-propanol, evaporated to dryness and chromatographed on 40 g SiO2 (ethyl acetae-hexane, 1:3) to yield 680 mg of 7,8-dichloro-6-methoxy-2-propyl-1-tetralone which melted at 127°-9° C. after recrystallization from ethyl acetate.

Provenance & Evidence