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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 867994Generated: October 30, 2026

2-[(3,4-Dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]acetonitrile → 2-[(3,4-Dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]ethanimidamide hydrochloride

https://huagongshe.com/reaction/867994

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(3,4-Dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]acetonitrileHCID 21289570—
Reactant(+)2-[(3,4-Dichloro-6,7,8,8a,9,10-hexahydro-8a-propyl-2-phenanthrenyl)oxy]acetonitrileHCID 21289578—
Product2-[(3,4-Dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]ethanimidamide hydrochlorideHCID 21289573—

Reaction Steps

By carrying out the reaction as described in Example 4, Step B, except that the racemic 2-[(3,4-dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]acetonitrile is replaced by an equal amount of (+)2-[(3,4-dichloro-6,7,8,8a,9,10-hexahydro-8a-propyl-2-phenanthrenyl)oxy]acetonitrile, there is obtained (+)2-[(3,4-dichloro-6,7,8,8a,9,10-hexahydro-6-oxo-8a-propyl-2-phenanthrenyl)oxy]ethanimidamide hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04777281
Source datasetuspto-grants-1988_10
ORD IDord-5b7c1ea9a1ff48bdbd0138caed251356
Source noteuspto-grants-1988_10