Diethyl (ethoxymethylene)malonate → HCID 14278965, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 4,5-bis(phenylmethoxy)-2-pyridinamine (8.7 g, 28.4 mmol) in diethyl ethoxymethylenemalonate (61.4 g, 284.0 mmol) was heated to 120° C. (bath temperature) for 2 hours. The major part of the diethyl ethoxymethylenemalonate was distilled off in vacuo and 100 ml of ether was added after cooling. The mixture was stored in the refrigerator overnight. The resulting crystals were filtered off with suction, washed with ether and dried in vacuo. Yield: 10.81 g; melting point 117.3° C.

Provenance & Evidence