Diphenyl Ether → HCID 14278966, compound

Participants

Reaction Conditions

Reaction Steps

At 225° C. [[[4,5-bis(phenylmethoxy)-2-pyridinyl]amino]methylene]malonic acid, diethyl ester (10.7 g, 22.45 mmol) was added to 135 g of diphenylether. After stirring for 30 minutes at 225° C., the mixture was allowed to cool at room temperature, and 150 ml of petroleum ether was added. After standing overnight in the refrigerator, the resulting crystals were collected by filtration, washed with petroleum ether and recrystallized from ethanol. Yield: 4.77 g; melting point 175.3° C.

Provenance & Evidence