HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanethiol → 2-(Ethylthio)-5-nitropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanethiol | HCID 6343 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(Ethylthio)-5-nitropyridine | HCID 10797571 | 86.1% |
Reaction Steps
2-Ethylthio-5-nitropyridine (5.0 g) is prepared in substantially the same manner as in the first paragraph of Reference Example 4, using 5.0 g of 2-chloro-5-nitropyridine, 2.0 g of ethyl mercaptan, 1.4 g of sodium hydride (about 60%, in oil), and 20 ml of dry tetrahydrofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04778796 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-73a1bdca55bc45eab376b4128e26993f |
| Source note | uspto-grants-1988_10 |