HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-(Pyridin-3-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-(3-Pyridinyl)-2-propenoic acid | HCID 101984 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(Pyridin-3-yl)propanoic acid | HCID 259624 | 100.6% |
Reaction Steps
A mixture of 5.0 g of 3-(3-pyridyl)acrylic acid, 0.4 g of 10% palladium on activated carbon, 150 ml of methanol, and 50 ml of dimethylformamide is hydrogenated at room temperature and atmospheric pressure. After removal of the catalyst by filtration, the filtrate is concentrated to give 5.1 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04778796 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-a5f614de024d446ca0de8b6149f15655 |
| Source note | uspto-grants-1988_10 |