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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 868371Generated: October 31, 2026

Methanol → N-(N-Formyl-L-alpha-aspartyl)-3-phenyl-L-alanine

https://huagongshe.com/reaction/868371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantL-PhenylalanineHCID 6140—
ReactantN-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamideHCID 11298025—
SolventWaterHCID 962—
ProductN-(N-Formyl-L-alpha-aspartyl)-3-phenyl-L-alanineHCID 92472—

Reaction Steps

In the process of the present invention, N-formyl-L-aspartic acid anhydride is condensated with L-phenylalanine in water or water containing methanol at a pH in the range of 7-12 to form N-formyl-α-L-aspartyl-L-phenylalanine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04778916
Source datasetuspto-grants-1988_10
ORD IDord-7c7477ec67fb49ad85c779572663cfd7
Source noteuspto-grants-1988_10