Aniline → HCID 21288482, compound

HRID 868422Notes

Reaction equation

HRID 868422 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:8][CH:9]([C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH2:18]Br)[CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]>>[OH:8][CH:9]([C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][CH:22]=1)[CH2:18][NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 6115AnilineHCID 21288526HCID 21288526, compound

Product 1

HCID 21288482HCID 21288482, compound

Procedure

For compounds in which X is --NR2 --(CHR1)n --, the corresponding amino starting compounds are employed to form the desired amino compound. Thus, aniline is condensed with 3-(1-hydroxyhexyl)benzylbromide to form 2-[3-(1-hydroxyhexyl)benzylamino]benzene. Alternatively, benzyl bromide is condensed with 3-(1-hydroxyhexyl)aniline to form 2-[3-(1-hydroxyhexyl)anilinomethyl]benzene.

Sources & evidence

ORD record
ord-5512a96a58d946ba92356ead8ad898ba
Source dataset
uspto-grants-1988_10
Patent number
US04778931

Reaction notes

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