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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 868477Generated: October 26, 2026

3-Fluoro-4-methoxybiphenyl → 3'-Fluoro-4'-methoxy-4-acetylbiphenyl

https://huagongshe.com/reaction/868477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methoxybiphenylHCID 14122124—
Reactantacetyl chloride AlCl3HCID 86587523—
SolventCarbon DisulfideHCID 6348—
Product3'-Fluoro-4'-methoxy-4-acetylbiphenylHCID 1438864882%

Reaction Steps

3-Fluoro-4-methoxybiphenyl was acetylated with acetyl chloride/AlCl3 in carbon disulfide in the usual way. The product was twice recrystallized from toluene to obtain 3'-fluoro-4'-methoxy-4-acetylbiphenyl (yield: 82%), m.p. 149°~149.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04780242
Source datasetuspto-grants-1988_10
ORD IDord-30fae1fe52f3476ea41d2f55fafdb1e8
Source noteuspto-grants-1988_10