HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 868514Generated: October 25, 2026
Triethyl orthoacetate → 4-Chloro-1-methyl[1,2,4]triazolo[4,3-a]quinoxaline
https://huagongshe.com/reaction/868514
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl orthoacetate | HCID 66221 | — |
| Reactant | 2-Chloro-3-hydrazinoquinoxaline | HCID 3658820 | — |
| Product | 4-Chloro-1-methyl[1,2,4]triazolo[4,3-a]quinoxaline | HCID 2768643 | — |
Reaction Steps
A reaction mixture of 5 g of 2-chloro-3-hydrazinoquinoxaline in 50 ml of triethyl orthoacetate was heated at 100° C. for three hours. Upon cooling, the precipitated solid was filtered, washed with cyclohexane, and dried affording 4.27 g of 4-chloro-1-methyl[1,2,4]triazolo[4,3-a]quinoxaline having a mp of 215°-218° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04780464 |
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| Source dataset | uspto-grants-1988_10 |
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| ORD ID | ord-2e1c081b3c124ed88f2757f390ecb8b8 |
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| Source note | uspto-grants-1988_10 |
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