2-Chloroethyldiisopropylammonium chloride → HCID 13934414, compound

HRID 868564Notes

Reaction equation

HRID 868564 reaction equation
[C:1]([NH:4][C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[C:8]2=[O:15])(=[O:3])[CH3:2].Cl.[CH:17]([N:20]([CH:24]([CH3:26])[CH3:25])[CH2:21][CH2:22]Cl)([CH3:19])[CH3:18]>>[C:1]([NH:4][C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:22][CH2:21][N:20]([CH:24]([CH3:26])[CH3:25])[CH:17]([CH3:19])[CH3:18])[C:9](=[O:14])[C:8]2=[O:15])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 779422-Chloroethyldiisopropylammonium chlorideHCID 21287240HCID 21287240, compound

Product 1

HCID 13934414HCID 13934414, compoundYield 77%

Procedure

By using 5-acetamidoisatin and 2-diisopropylaminoethyl chloride hydrochloride, a method analogous to that described in Reference Example 7 was carried out to obtain 5-acetamido-1-(2-diisopropylaminoethyl)isatin having a melting point of 187°-190° C. (yield: 77.0%, recrystallizing solvent: ethyl acetate-hexane).

Sources & evidence

ORD record
ord-43f592b7d7e94679bb5bf9f72ec55c26
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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