2-Chloroethyldiisopropylammonium chloride → HCID 13934419, compound

HRID 868568Notes

Reaction equation

HRID 868568 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH3:13])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8](=[O:11])[C:7]2=[O:12].Cl.[CH:15]([N:18]([CH:22]([CH3:24])[CH3:23])[CH2:19][CH2:20]Cl)([CH3:17])[CH3:16]>>[Br:1][C:2]1[CH:3]=[C:4]([CH3:13])[CH:5]=[C:6]2[C:10]=1[N:9]([CH2:20][CH2:19][N:18]([CH:22]([CH3:24])[CH3:23])[CH:15]([CH3:17])[CH3:16])[C:8](=[O:11])[C:7]2=[O:12]

Participants

3

Reactant 2

HCID 779422-Chloroethyldiisopropylammonium chlorideHCID 6116217-Bromo-5-methylindoline-2,3-dione

Product 1

HCID 13934419HCID 13934419, compoundYield 13.1%

Procedure

By using the 7-bromo-5-methylisatin and 2-diisopropylaminoethyl chloride hydrochloride, a method analogous to that described in Reference Example 1 was carried out to obtain 7-bromo-1-(2-diisopropylaminoethyl)-5-methylisatin having a melting point of 94°-97° C. (yield: 13.1%).

Sources & evidence

ORD record
ord-c46dc9e9b9d5495b9cdb70046daff00a
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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