HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 1-[2-(N-isopropylbenzylamino)ethyl]isatin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | N-benzyl-N-(2-chloroethyl)propan-2-amine | HCID 48358 | — |
| Product | 1-[2-(N-isopropylbenzylamino)ethyl]isatin | HCID 54367399 | — |
Reaction Steps
By using isatin and the 2-(N-isopropylbenzylamino)ethyl chloride, a method analogous to that described in Reference Example 7 was carried out, and the reaction product was purified with silica gel column chromatography (eluent: chloroform) to obtain 1-[2-(N-isopropylbenzylamino)ethyl]isatin in an oil (yield: 43.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04780477 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-76f01a9d89844f46acebacb597d71f37 |
| Source note | uspto-grants-1988_10 |