Semicarbazide hydrochloride → HCID 178457307, compound

HRID 868587Notes

Reaction equation

[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH2:6][CH2:7][N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:11](=O)[C:9]1=[O:10])([CH3:3])[CH3:2].Cl.[NH2:23][NH:24][C:25]([NH2:27])=[O:26]>>[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH2:6][CH2:7][N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)/[C:11](=[N:23]\[NH:24][C:25]([NH2:27])=[O:26])/[C:9]1=[O:10])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 11236Semicarbazide hydrochloride

HCID 139344201-(3-Diisopropylaminopropyl)isatin

Product 1

HCID 178457307HCID 178457307, compoundYield 66.6%

Procedure

By using 1-(3-diisopropylaminopropyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 4 was carried out to obtain (E)-1-(3-diisopropylaminopropyl)isatin 3-semicarbazone having a melting point of 173°-175° C. (yield: 66.6%, recrystallizing solvent: methanol-benzene).

Sources & evidence

ORD record: ord-6afa26a8e286416c9d4a471013b50dce
Source dataset: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04780477

Reaction notes

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