Semicarbazide hydrochloride → HCID 178457219, compound

HRID 868589Notes

Reaction equation

HRID 868589 reaction equation
[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH:5]([CH3:18])[CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[NH2:23][NH:24][C:25]([NH2:27])=[O:26]>>[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH:5]([CH3:18])[CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)/[C:10](=[N:23]\[NH:24][C:25]([NH2:27])=[O:26])/[C:8]1=[O:9])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11236Semicarbazide hydrochlorideHCID 13934422HCID 13934422, compound

Product 1

HCID 178457219HCID 178457219, compoundYield 77.6%

Procedure

By using 1-(2-diisopropylaminopropyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out, and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-diisopropylaminopropyl)isatin 3-semicarbazone having a melting point of 201°-204° C. (yield: 77.6%).

Workup

  1. customthe reaction product was recrystallized from ethanol

Sources & evidence

ORD record
ord-eaefe22859c5404a99e9395ebe17f694
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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