Acetone → (6-Allyloxy-7-methoxy-quinazolin-4-yl)-(4-chloro-phenyl)-amine

HRID 86859Notes

Reaction equation

HRID 86859 reaction equation
[CH2:28]([CH:29]=[CH2:30])[Br:31].[CH3:32][C:33](=[O:34])[CH3:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:20][CH3:21])[c:16]([OH:19])[cH:17][c:18]23)[cH:6][cH:7]1.[K+:22].[K+:23].[O-:24][C:25]([O-:26])=[O:27]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][c:15]([O:20][CH3:21])[c:16]([O:19][CH2:30][CH:29]=[CH2:28])[cH:17][c:18]23)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 7841Allyl bromideHCID 19660Carbonate IonHCID 21098391HCID 21098391, compound

Product 1

HCID 21098403(6-Allyloxy-7-methoxy-quinazolin-4-yl)-(4-chloro-phenyl)-amine

Sources & evidence

ORD record
ord-aa4d44a0e871449ea0124022314a9741
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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