Semicarbazide hydrochloride → HCID 178423605, compound

HRID 868593Notes

Reaction equation

[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][C:16]=2[CH3:18])[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[NH2:23][NH:24][C:25]([NH2:27])=[O:26]>>[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][C:16]=2[CH3:18])/[C:10](=[N:23]\[NH:24][C:25]([NH2:27])=[O:26])/[C:8]1=[O:9])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 11236Semicarbazide hydrochloride

HCID 13934410HCID 13934410, compound

Product 1

HCID 178423605HCID 178423605, compoundYield 75.7%

Procedure

By using 1-(2-diisopropylaminoethyl)-7-methylisatin and semicarbazide hydrochloride, a method analogous to that described in Example 4 was carried out to obtain (E)-1-(2-diisopropylaminoethyl)-7-methylisatin 3-semicarbazone having a melting point of 194°-195° C. (yield: 75.7%).

Sources & evidence

ORD record: ord-e489205a7bc241ff8497f597c92241e0
Source dataset: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04780477

Reaction notes

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