Semicarbazide hydrochloride → HCID 178497445, compound

Participants

Reaction Steps

By using methyl 1-(2-diisopropylaminoethyl)-7-isatincarboxylate and semicarbazide hydrochloride, a method analogous to that described in Example 6 was carried out, and the reaction product was purified with silica gel column chromatography (eluent: chloroform/ethanol=20/1) and then recrystallized from chloroform-hexane to obtain (Z)-1-(2-diisopropylaminoethyl)-7-methoxycarbonylisatin 3-semicarbazone having a melting point of 192°-195° C. (yield: 28.1%).

Provenance & Evidence