Semicarbazide hydrochloride → HCID 178457375, compound

HRID 868605Notes

Reaction equation

HRID 868605 reaction equation
[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[NH2:19][NH:20][C:21]([NH2:23])=[O:22]>>[CH:1]([NH:4][CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)/[C:10](=[N:19]\[NH:20][C:21]([NH2:23])=[O:22])/[C:8]1=[O:9])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11236Semicarbazide hydrochlorideHCID 21287238HCID 21287238, compound

Product 1

HCID 178457375HCID 178457375, compoundYield 49.8%

Procedure

By using 1-(2-isopropylaminoethyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out, and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-isopropylaminoethyl)isatin 3-semicarbazone having a melting point of 169°-172° C. (decomposition) (yield: 49.8%).

Workup

  1. customthe reaction product was recrystallized from ethanol

Sources & evidence

ORD record
ord-ec806857fa414720b0039066eb587a42
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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