Sodium Hydroxide → HCID 23699968, compound

HRID 868629Notes

Reaction equation

HRID 868629 reaction equation
[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([C:6]([C:8]2[C:16]3[O:15][CH:14]=[CH:13][C:12]=3[CH:11]=[C:10]([CH2:17][C:18]([OH:20])=[O:19])[CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[OH-].[Na+:24]>CO>[Cl:1][C:2]1[CH:22]=[CH:21][C:5]([C:6]([C:8]2[C:16]3[O:15][CH:14]=[CH:13][C:12]=3[CH:11]=[C:10]([CH2:17][C:18]([O-:20])=[O:19])[CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[Na+:24]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 13704398HCID 13704398, compound

Product 1

HCID 23699968HCID 23699968, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 250 mg of (7-(4-chlorobenzoyl)benzofuran-5-ylacetic acid in 5 ml of methanol is added 1 molar equivalent of sodium hydroxide in the form of 0.1N solution. The solvent is evaporated to dryness and the residue taken up in 2 ml of methanol, followed by precipitation with ether, to yield sodium 7-(4-chlorobenzoyl)benzofuran-5-ylacetate.

Workup

  1. customThe solvent is evaporated to dryness
  2. customfollowed by precipitation with ether

Sources & evidence

ORD record
ord-7da490fb642b4213a64892597972aefe
Source dataset
uspto-grants-1988_10
Patent number
US04780480

Reaction notes

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