HCID 22840271, compound → HCID 14151468, compound

Participants

Reaction Steps

N-Benzyloxycarbonyl-D-prolyl-α-L-aspartyl-L-phenylalanine methyl ester (2.6 g) was dissolved in 100 ml of 80% aqueous acetic acid, and the solution was subjected to catalytic reduction in a hydrogen gas stream at room temerature for four hours using palladium/carbon as catalyst. After filtering off the catalyst, the filtrate was concentrated to dryness under reduced pressure, affording 1.7 g of white powder. M.p.: 238°-241.5° C.

Provenance & Evidence