4-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate → alpha-L-Aspartyl-D-alanine propyl ester

HRID 868649Notes

Reaction equation

HRID 868649 reaction equation
[CH2:1]([O:4][C:5](=[O:9])[C@@H:6]([CH3:8])[NH2:7])[CH2:2][CH3:3].[NH:10](C(OCC1C=CC=CC=1)=O)[C@H:11]([C:23](O)=[O:24])[CH2:12][C:13](=[O:22])[O:14]CC1C=CC=CC=1>>[CH2:1]([O:4][C:5](=[O:9])[C@@H:6]([CH3:8])[NH:7][C:23](=[O:24])[C@H:11]([CH2:12][C:13](=[O:14])[OH:22])[NH2:10])[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 476024-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartateHCID 45086593Propyl D-alaninate

Product 1

HCID 22840262alpha-L-Aspartyl-D-alanine propyl ester

Procedure

This compound was prepared from 1.7 g D-alanine propyl ester and 3.6 g Z-Asp(OBzl) in a manner similar to Example 11 (A). Yield: 1.6 g.

Sources & evidence

ORD record
ord-703c30c6b0e34bf39aa0d29269011805
Source dataset
uspto-grants-1988_10
Patent number
US04780528

Reaction notes

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