4-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate → alpha-L-aspartyl-D-serine isopropyl ester

HRID 868652Notes

Reaction equation

HRID 868652 reaction equation
Cl.[CH:2]([O:5][C:6](=[O:11])[C@@H:7]([CH2:9][OH:10])[NH2:8])([CH3:4])[CH3:3].[NH:12](C(OCC1C=CC=CC=1)=O)[C@H:13]([C:25](O)=[O:26])[CH2:14][C:15](=[O:24])[O:16]CC1C=CC=CC=1>>[CH:2]([O:5][C:6](=[O:11])[C@@H:7]([CH2:9][OH:10])[NH:8][C:25](=[O:26])[C@H:13]([CH2:14][C:15](=[O:16])[OH:24])[NH2:12])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 476024-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartateHCID 11819713D-serine isopropyl ester hydrochloride

Product 1

HCID 22840263alpha-L-aspartyl-D-serine isopropyl ester

Procedure

This compound was prepared from 1.8 g D-serine isopropyl ester hydrochloride and 3.6 g Z-Asp(OBzl) in a manner similar to Example 16 (A). Yield: 1.9 g.

Sources & evidence

ORD record
ord-8cd0a1c9d9ce4921bad3ff9296c6b96c
Source dataset
uspto-grants-1988_10
Patent number
US04780528

Reaction notes

Loading…