4-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate → alpha-L-Aspartyl-D-alanine propyl ester

HRID 868658Notes

Reaction equation

HRID 868658 reaction equation
Cl.[CH2:2]([O:5][C:6](=[O:10])[C@@H:7]([CH3:9])[NH2:8])[CH2:3][CH3:4].[NH:11](C(OCC1C=CC=CC=1)=O)[C@H:12]([C:24](O)=[O:25])[CH2:13][C:14](=[O:23])[O:15]CC1C=CC=CC=1>>[CH2:2]([O:5][C:6](=[O:10])[C@@H:7]([CH3:9])[NH:8][C:24](=[O:25])[C@H:12]([CH2:13][C:14](=[O:15])[OH:23])[NH2:11])[CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 476024-(Phenylmethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-aspartateHCID 88117377d-Alanine n-propyl ester hydrochloride

Product 1

HCID 22840262alpha-L-Aspartyl-D-alanine propyl ester

Procedure

This compound was prepared from 1.8 g D-alanine n-propyl ester hydrochloride and 3.6 g Z-Asp(OBzl) in a manner similar to Example 16 (A). Yield: 1.9 g.

Sources & evidence

ORD record
ord-510405ec289a4df39481f48732bffc54
Source dataset
uspto-grants-1988_10
Patent number
US04780528

Reaction notes

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