1,2,4-Oxadiazole, 5-cyclopropyl-3-(isocyanomethyl)- → HCID 21287687, compound

HRID 868672Notes

Reaction equation

HRID 868672 reaction equation
[CH3:1][N:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[I:13])[NH:4][C:3]1=O.[CH:15]1([C:18]2[O:22][N:21]=[C:20]([CH2:23][N+:24]#[C-:25])[N:19]=2)[CH2:17][CH2:16]1>>[CH:15]1([C:18]2[O:22][N:21]=[C:20]([C:23]3[N:24]=[CH:25][N:4]4[C:5]5[C:10](=[C:9]([I:13])[CH:8]=[CH:7][CH:6]=5)[C:11](=[O:12])[N:2]([CH3:1])[C:3]=34)[N:19]=2)[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 107493421,2,4-Oxadiazole, 5-cyclopropyl-3-(isocyanomethyl)-HCID 21287671HCID 21287671, compound

Product 1

HCID 21287687HCID 21287687, compound

Procedure

M.p. 217°-220° C. by reaction between 3-methyl-5-iodo-1,2,3,4-tetrahydro-2,4-dioxo-quinazoline and 5-cyclopropyl-3-isocyanomethyl-1,2,4-oxadiazole.

Sources & evidence

ORD record
ord-4a4ad6b80a954e66ac6a27676f567928
Source dataset
uspto-grants-1988_10
Patent number
US04780539

Reaction notes

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