HCID 19784294, compound → 3-(5-Cyclopropyl-1,2,4-oxadiazol-3yl)-4,5-dihydro-4-methyl5-oxo-imidazo(1,5-a)quinazoline

HRID 868674Notes

Reaction equation

HRID 868674 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[N:8]=[CH:9][N:10]3[C:19]4[C:14](=[C:15](C(F)(F)F)[CH:16]=[CH:17][CH:18]=4)[C:13](=[O:24])[N:12]([CH3:25])[C:11]=23)[N:3]=1.[CH3:26][C:27]1ON=C(C[N+]#[C-])N=1>>[CH:1]1([C:2]2[O:6][N:5]=[C:4]([C:7]3[N:8]=[CH:9][N:10]4[C:19]5[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=5)[C:13](=[O:24])[N:12]([CH3:25])[C:11]=34)[N:3]=2)[CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 19784294HCID 19784294, compoundHCID 212876843-(5-Methyl-1,2,4-oxadiazol-3-yl)-4,5-dihydro-4-methyl-5-oxo-6-trifluoromethyl-imidazo(1,5-a)quinazoline

Product 1

HCID 212876933-(5-Cyclopropyl-1,2,4-oxadiazol-3yl)-4,5-dihydro-4-methyl5-oxo-imidazo(1,5-a)quinazoline

Procedure

3-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-dihydro-4-methyl-5-oxo-6-trifluoromethyl-imidazo(1,5-a)quinazoline, M.p. 251.5°-251.9° C., by reaction between 3-methyl-5-trifluoromethyl 1 2,3,4-tetrahydro-2,4-dioxo-quinazoline and 5-methyl-3-isocyanomethyl-1,2,4-oxadiazole.

Sources & evidence

ORD record
ord-ea07f2c52f274b99912307e536062cd4
Source dataset
uspto-grants-1988_10
Patent number
US04780539

Reaction notes

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