Methanol → 6,8-Di-t-butyl-2-hydroxycarbonylchroman

HRID 86885Notes

Reaction equation

HRID 86885 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[c:12]([c:13]([C:15]([CH3:16])([CH3:17])[CH3:18])[cH:14]1)[O:11][CH:10]([C:19](=[O:20])[O:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:9][CH2:8]2.[CH3:28][OH:29].[CH3:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[Na+:27].[OH-:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]2[c:12]([c:13]([C:15]([CH3:16])([CH3:17])[CH3:18])[cH:14]1)[O:11][CH:10]([C:19](=[O:20])[OH:21])[CH2:9][CH2:8]2

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 1140TolueneHCID 113599626,8-Di-t-butyl-2-butoxycarbonylchroman

Product 1

HCID 99658046,8-Di-t-butyl-2-hydroxycarbonylchroman

Sources & evidence

ORD record
ord-616498fd8bab4340805d56ac8420393d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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