1-(3-Aminobenzo[B]thiophen-2-YL)ethanone → (E)-2-cinnamoyl-3-amino-6-fluoro-benzo[b]thiophene

HRID 869420Notes

Reaction equation

HRID 869420 reaction equation
[NH2:1][C:2]1[C:3]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][C:4]=2[S:5][C:6]=1[C:7](=[O:9])[CH3:8].N[C:16]1[C:17]2[CH:27]=[CH:26][CH:25]=[CH:24][C:18]=2SC=1C(=O)C>>[C:7]([C:6]1[S:5][C:4]2[CH:10]=[C:11]([F:14])[CH:12]=[CH:13][C:3]=2[C:2]=1[NH2:1])(=[O:9])/[CH:8]=[CH:16]/[C:17]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:18]=1

Participants

3

Reactant 2

HCID 34342391-(3-Aminobenzo[B]thiophen-2-YL)ethanoneHCID 86722267Ethanone, 1-(3-amino-6-fluorobenzo[b]thien-2-yl)-

Product 1

HCID 86722266(E)-2-cinnamoyl-3-amino-6-fluoro-benzo[b]thiophene

Procedure

The procedure was similar to step S3C, while the starting material was 17B in stead of 3B.

Sources & evidence

ORD record
ord-21f0ccd74d854158a89c94db9ce12426
Source dataset
uspto-grants-2015_03
Patent number
US08969373B2

Reaction notes

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