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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869428Generated: October 30, 2026

2-Hydroxybenzonitrile → 8-Methoxy-6H-11-oxa-6-aza-benzo[a]fluoren-5-one

https://huagongshe.com/reaction/869428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-HydroxybenzonitrileHCID 11907—
Reactant2-Hydroxy-5-methoxybenzonitrileHCID 7022529—
Reactant2-(2-Methoxycarbonyl-phenyl)-2-bromo-acetic acid methyl esterHCID 11507511—
Reactant2-(4-Chloro-2-methoxycarbonyl-phenyl)-2-bromo-acetic acid methyl esterHCID 86722271—
Product8-Methoxy-6H-11-oxa-6-aza-benzo[a]fluoren-5-oneHCID 11637529—

Reaction Steps

The procedure was similar to step S19B, while the starting material 19A and 2-hydroxy-benzonitrile were replaced with 21A and 2-hydroxy-5-methoxy-benzonitrile, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969373B2
Source datasetuspto-grants-2015_03
ORD IDord-f899e1f151774b99a8ce031e439e6542
Source noteuspto-grants-2015_03