8-Methoxy-6H-11-oxa-6-aza-benzo[a]fluoren-5-one → 8-Methoxy-5-chloro-benzofuro[3,2-c]isoquinoline

HRID 869429Notes

Reaction equation

HRID 869429 reaction equation
O[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]2[O:12][C:13]3[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][C:14]=3[C:4]=2[N:3]=1.[Cl:21]C1C=C2C(C3OC4C=CC=CC=4C=3N=C2O)=CC=1>>[CH3:20][O:19][C:16]1[CH:17]=[CH:18][C:13]2[O:12][C:5]3[C:6]4[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=4)[C:2]([Cl:21])=[N:3][C:4]=3[C:14]=2[CH:15]=1

Participants

3

Reactant 2

HCID 116375298-Methoxy-6H-11-oxa-6-aza-benzo[a]fluoren-5-oneHCID 1785169623-Chloro-benzofuro[3,2-c]isoquinoline-5-ol

Product 1

HCID 867222768-Methoxy-5-chloro-benzofuro[3,2-c]isoquinoline

Procedure

The procedure was similar to step S19C, while the starting material was 21B in stead of 19B.

Sources & evidence

ORD record
ord-679838f023bc45c5b1ec307ae3dac856
Source dataset
uspto-grants-2015_03
Patent number
US08969373B2

Reaction notes

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