2-Hydroxybenzonitrile → HCID 178516963, compound

HRID 869431Notes

Reaction equation

HRID 869431 reaction equation
COC(=O)[CH:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12](OC)=[O:13])Br.COC(=O)C(C1C=CC(Cl)=CC=1C(OC)=O)Br.[SH:34][C:35]1[CH:42]=[CH:41][CH:40]=[CH:39][C:36]=1[C:37]#[N:38].OC1C=CC=CC=1C#N>>[OH:13][C:12]1[C:7]2[C:6](=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:4]2[S:34][C:35]3[CH:42]=[CH:41][CH:40]=[CH:39][C:36]=3[C:37]=2[N:38]=1

Participants

5

Reactant 4

HCID 119072-HydroxybenzonitrileHCID 110189262-MercaptobenzonitrileHCID 11507511HCID 11507511, compoundHCID 86722271HCID 86722271, compound

Product 1

HCID 178516963HCID 178516963, compound

Procedure

The procedure was similar to step S19B, while the starting material was 23A in stead of 19A, and used 2-mercapto-benzonitrile in stead of 2-hydroxy-benzonitrile.

Sources & evidence

ORD record
ord-66b1066b194f43198cd40cfd42b7ca8f
Source dataset
uspto-grants-2015_03
Patent number
US08969373B2

Reaction notes

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