3-Chloro-benzofuro[3,2-c]isoquinoline-5-ol → 5,8-Dichlorobenzofuro[3,2-c]isoquinoline

HRID 869434Notes

Reaction equation

HRID 869434 reaction equation
O[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]2[O:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[C:4]=2[N:3]=1.[Cl:20]C1C=C2C(C3OC4C=CC=CC=4C=3N=C2O)=CC=1>>[Cl:20][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]2[O:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 1785169623-Chloro-benzofuro[3,2-c]isoquinoline-5-olHCID 178516965HCID 178516965, compound

Product 1

HCID 867222785,8-Dichlorobenzofuro[3,2-c]isoquinoline

Procedure

The procedure was similar to step S19C, while the starting material was 24B in stead of 19B.

Sources & evidence

ORD record
ord-b75646df2d5642698cf96a07be7c32c7
Source dataset
uspto-grants-2015_03
Patent number
US08969373B2

Reaction notes

Loading…