HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22663198, compound → HCID 86721352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22663198 | HCID 22663198 | — |
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Product | HCID 86721352 | HCID 86721352 | 54% |
Reaction Steps
Using 4-methoxy-2-propyl-1H-benzo[d]imidazole (Journal of Pharmacy and Pharmacology; 1956, vol. 8, p 661, 338 mg, 1.78 mmol) and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (700 mg, 1.95 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (448 mg, 54%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-228eeda5426e4ad895e4cb2bc89841fd |
| Source note | uspto-grants-2015_03 |