HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile → HCID 86721356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Reactant | HCID 86721357 | HCID 86721357 | — |
| Product | HCID 86721356 | HCID 86721356 | 92% |
Reaction Steps
[step 2] Using (2-propyl-1H-benzo[d]imidazol-4-yl)methanol (47 mg, 0.25 mmol) obtained in step 1 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (92 mg, 0.26 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (106 mg, 92%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-afe6d35baafe46f188d6480c623a301c |
| Source note | uspto-grants-2015_03 |