HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile → HCID 86721360, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Reactant | HCID 86721361 | HCID 86721361 | — |
| Product | HCID 86721360 | HCID 86721360 | 91% |
Reaction Steps
[step 4] Using [2-(methoxymethyl)-1H-benzo[d]imidazol-4-yl]methanol (203 mg, 1.06 mmol) obtained in step 3 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (386 mg, 1.08 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (451 mg, 91%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-1b464b3f563e430cb0c69e31d15af6d3 |
| Source note | uspto-grants-2015_03 |