HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 64722912, compound → HCID 86721362, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 64722912 | HCID 64722912 | — |
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Product | HCID 86721362 | HCID 86721362 | 90.3% |
Reaction Steps
[step 3] Using 4-chloro-2-(methoxymethyl)-1H-benzo[d]imidazole (50 mg, 0.25 mmol) obtained in step 2 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (96 mg, 0.27 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (107 mg, 89%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-191571d6ea044ece8791b62fc454643e |
| Source note | uspto-grants-2015_03 |