HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile → HCID 86721373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Reactant | HCID 178478246 | HCID 178478246 | — |
| Product | HCID 86721373 | HCID 86721373 | 62.8% |
Reaction Steps
Using 7-chloro-2-cyclobutyl-3H-imidazo[4,5-b]pyridine (WO2009/29592, 69 mg, 0.335 mmol) and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (120 mg, 0.335 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (102 mg, 62%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-4fdf7cfb72b94ddcb84f2c4dcda45938 |
| Source note | uspto-grants-2015_03 |