2-cyclopropyl-1H-1,3-benzodiazole → (E)-2-cyclopropyl-2-{8-[(2-cyclopropyl-1H-benzo[d]imidazol-1-yl)methyl]-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene)acetonitrile

참여 물질

반응 단계

Using 2-cyclopropyl-1H-benzo[d]imidazole (European Journal of Organic Chemistry, 2000, p 1229, 58 mg, 0.33 mmol) and (E)-2-(8-bromomethyl-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene)-2-cyclopropylacetonitrile (120 mg, 0.31 mmol) obtained in Reference Example 6, and in the same manner as in Reference Example 1A, the title compound (133 mg, 93%) was obtained.

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