HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile → HCID 86721444, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Reactant | HCID 178437563 | HCID 178437563 | — |
| Product | HCID 86721444 | HCID 86721444 | 92.9% |
Reaction Steps
Using 2-ethyl-4-phenyl-1H-imidazole (Tetrahedron Letters, 1967, p 265, 47 mg, 0.273 mmol) and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (90 mg, 0.273 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (114 mg, 92%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-1857ea6f725e49b0b0d7a9dc5b50ea92 |
| Source note | uspto-grants-2015_03 |