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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869645Generated: October 25, 2026

(R)-ethyl 3-(pyrrolidin-2-ylmethoxy)picolinate → HCID 178470240, compound

https://huagongshe.com/reaction/869645

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-ethyl 3-(pyrrolidin-2-ylmethoxy)picolinateHCID 86666098—
ReactantHCID 178493765HCID 178493765—
ReactantHCID 178525710HCID 178525710—
ProductHCID 178470240HCID 178470240—

Reaction Steps

The title compound was prepared according to the procedure described in Step 5 of EXAMPLE 31 using (R)-ethyl 3-(pyrrolidin-2-ylmethoxy)picolinate bis(trifluoroactetic acid) salt (EXAMPLE 34 Step 1) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of ammonium chloride and 5-methoxy-3-(((R)-1-(trans-4-(trifluoromethyl)cyclohexanecarbonyl)pyrrolidin-2-yl)methoxy)picolinic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-e4774ec360ad450e83d9eaceb53b2ca0
Source noteuspto-grants-2015_03