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HRID869650

反应详情

EQUATION

反应方程式

HRID 869650 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)CC1CCC(F)(F)CC1
HCID53420743

(4,4-Difluorocyclohexyl)acetic acid

C8H12F2O2

结构：CCOC(=O)c1ncccc1OC[C@H]1CCCN1
HCID86666098

未命名化合物

结构：COc1cnc(C(=O)O)c(OC[C@H]2CCCN2C(=O)[C@H]2CC[C@H](C(F)(F)F)CC2)c1
HCID178493765

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1ncccc1OC[C@H]1CCCN1C(=O)CC1CCC(F)(F)CC1
HCID86666100

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Step 5 of EXAMPLE 31 using (R)-ethyl 3-(pyrrolidin-2-ylmethoxy)picolinate bis(trifuluoroacetic acid) salt (EXAMPLE 34 Step 1) and 2-(4,4-difluorocyclohexyl)acetic acid instead of ammonium chloride and 5-methoxy-3-(((R)-1-(trans-4-(trifluoromethyl)cyclohexanecarbonyl)pyrrolidin-2-yl)methoxy)picolinic acid.