돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 869658생성일: 2026년 10월 25일

3-Hydroxy-5-chloropyridine → ethyl 3-(((2R,4R)-4-(benzyloxymethoxy)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinate

https://huagongshe.com/reaction/869658

반응식

참여 물질

역할이름HCID투입량
반응물3-Hydroxy-5-chloropyridineHCID 582305—
반응물Ethyl 3-hydroxypicolinateHCID 15080989—
반응물(2R,4R)-tert-butyl 4-(benzyloxymethoxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylateHCID 66961725—
생성물ethyl 3-(((2R,4R)-4-(benzyloxymethoxy)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinateHCID 66962068—

반응 단계

The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 29 using (2R,4R)-tert-butyl 4-(benzyloxymethoxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate (EXAMPLE 79 Step 2) and ethyl 3-hydroxypicolinate instead of (R)-pyrrolidin-2-ylmethanol and 5-chloropyridin-3-ol.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08969383B2
출처 데이터셋uspto-grants-2015_03
ORD IDord-3f9705338f904d2185b0f25ba8053b6d
출처 메모uspto-grants-2015_03