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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869660Generated: October 31, 2026

Indole-2-carboxylic acid → HCID 178470241, compound

https://huagongshe.com/reaction/869660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-2-carboxylic acidHCID 72899—
Reactantethyl 3-(((2R,4R)-4-(benzyloxymethoxy)pyrrolidin-2-yl)methoxy)picolinateHCID 66962098—
ReactantHCID 178525710HCID 178525710—
ProductHCID 178470241HCID 178470241—

Reaction Steps

The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 3 using ethyl 3-(((2R,4R)-4-(benzyloxymethoxy)pyrrolidin-2-yl)methoxy)picolinate (EXAMPLE 79 Step 4) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride and indole-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-891454e50ed14a6ba29f7531a2576aa5
Source noteuspto-grants-2015_03