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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869662Generated: October 31, 2026

3-Isoxazolamine → HCID 178522359, compound

https://huagongshe.com/reaction/869662

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IsoxazolamineHCID 1810216—
Reactant(R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochlorideHCID 66960633—
ReactantHCID 178524886HCID 178524886—
ProductHCID 178522359HCID 178522359—

Reaction Steps

The title compound was prepared according to the procedure described in Step 4 of EXAMPLE 1 using 3-(((2R,4R)-4-(benzyloxymethoxy)-1-(trans-4-(trifluoromethyl)cyclohexanecarbonyl)pyrrolidin-2-yl)methoxy)picolinic acid (EXAMPLE 79 Step 6) and isoxazol-3-amine instead of cis-4-(trifluoromethyl)cyclohexanecarboxylic acid and (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-1cdc8f0e4e5f4195ba7ba00fc2e19d5f
Source noteuspto-grants-2015_03